Blar i forfatter "Wuxiuer, Yimingjiang"

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    • Comparative molecular dynamics simulations of mitogen-activated protein kinase-activated protein kinase 5 

      Lindin, Inger; Wuxiuer, Yimingjiang; Sylte, Ingebrigt; Ravna, Aina Westrheim; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5) 

      Lindin, Inger; Wuxiuer, Yimingjiang; Kufareva, Irina; Abagyan, Ruben; Moens, Ugo; Sylte, Ingebrigt; Ravna, Aina Westrheim (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Mitogen-activated protein kinase-activated protein kinase 5 (MK5) is involved in one of the major signaling pathways in cells, the mitogen-activated protein kinase pathway. MK5 was discovered in 1998 by the groups of Houng Ni and Ligou New, and was found to be highly conserved throughout the vertebrates. Studies, both in vivo and in vitro, have shown that it is implicated in tumor ...

    • Theoretical and experimental studies of thermolysin inhibition 

      Wuxiuer, Yimingjiang (Master thesis; Mastergradsoppgave, 2008-05-15)
      Zinc-metalloproteinases play a key role in the biosythesis and metabolism of different bioactive peptides. As a member of zinc-metalloproteinases, thermolysin has served as a model system to study the inhibition mechanism of other metalloproteinases. Inhibitors of thermolysin have considerable potential as therapeutic agents. In the present master thesis, docking calculations were performed and ...